DNA Methylation Profiles of Vegans and Non-Vegetarians in the Adventist Health Study-2 Cohort

Funded by the Ardmore Institute of Health and the National Institutes of Health, this paper sought to determine if DNA methylation patterns differed between vegans and non-vegetarians in the Adventist Health Study-2 cohort. A vegan diet was associated predominantly with hypomethylation of genes, most notably methyltransferase-like 1 (METTL1). The findings suggest modest differences in DNA methylation in vegans and non-vegetarians, with a much greater number of detectable significant differences expected with a larger sample.

Congratulations on publication, Dr. Fayth Miles and team (Andrew Mashchak, Valery Filippov, Michael Orlich, Penelope Duerksen-Hughes, Xin Chen, Charles Wang, Kimberly Siegmund, Gary Fraser)

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